Prevalence of Lymph Node Metastasis in Malignant Ovarian Germ Cell Tumors

Ovarian germ cell malignancy mostly occurs in the second decades of life, accounting for 5% of ovarian malignancies, and is mainly unilateral, although 1015% of dysgerminoma involve bilaterally (Gershenson, 2007; Bilici et al., 2014). Majority of this gynecologic malignancy has been very favorable outcomes, high chemosensitivity, and long-term survival. Successful surgery by fertility-preserving comprehensive approach, which means peritoneal cytology, meticulous pelvic and abdominal exploration, unilateral salpingo-ophorectomy, pelvic and para-aortic node dissection, omentectomy, and peritoneal biopsies to retain the uterus and contralateral normal ovary. In clinical early-stage of malignant ovarian germ cell tumors (MOGCT) had lymph nodes metastasis rate of 10-18% (Kumar et al., 2008; Mahdi et al., 2011; Kleppe et al., 2014). Lymph node metastasis is an independent predictor of poor survival in ovarian germ cell patients with a hazards ratio (HR) of 2.87 (95%CI 1.439-5.725)